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9 let, 7 měsíců #2697 | |
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Last viwd on xList 7/17/2015
Mdol (mthylpdnisolon) is a glucocoticoid (adnocotical stoid) that can dpss th immun spons and inlammation; it is usd o many disass and conditions. Mdol is availabl as 2, 4, 8, 16 o 32 mg stngth tablts. Dosags a xtmly vaiabl and a basd on what disass a bing tatd. Medrol us in pgnancy is not advisd; bnits vsus potntial poblms should b considd o pgnant womn. Medrol is not advisd o womn who a bast ding. Medrol has bn usd in pdiatic patints, but th dosag should b caully adjustd o ach patint and disas. Ou Mdol Sid cts Dug Cnt povids a comphnsiv viw o availabl dug inomation on th potntial sid cts whn taking this mdication. SID CTS: Nausa, vomiting, hatbun, hadach, dizzinss, toubl slping, apptit changs, incasd swating, o acn may occu. I any o ths cts psist o wosn, tll you docto o phamacist pomptly. mmb that you docto has pscibd this mdication bcaus h o sh has judgd that th bnit to you is gat than th isk o sid cts. Many popl using this mdication do not hav sious sid cts. This mdication may mak you blood suga lvl is, which can caus o wosn diabts. Tll you docto immdiatly i you dvlop symptoms o high blood suga, such as incasd thist and uination. I you alady hav diabts, b su to chck you blood sugas gulaly. You docto may nd to adjust you diabts mdication, xcis pogam, o dit. This mdication may low you ability to ight inctions. This may mak you mo likly to gt a sious (aly atal) inction o mak any inction you hav wos. Tll you docto ight away i you hav any signs o inction (such as v, chills, psistnt so thoat, cough, whit patchs in th mouth). Tll you docto ight away i you hav any sious sid cts, including: unusual wight gain, mnstual piod changs, bon/joint pain, asy buising/blding, mntal/mood changs (such as mood swings, dpssion, agitation), muscl waknss/pain, puy ac, slow wound haling, swlling o th ankls/t/hands, thinning skin, unusual hai/skin gowth, vision poblms, ast/slow/igula hatbat. This dug may inquntly caus sious (aly atal) blding om th stomach o intstins. I you notic any o th ollowing unlikly but sious sid cts, consult you docto o phamacist immdiatly: black/bloody stools, vomit that looks lik co gounds, psistnt stomach/abdominal pain. Gt mdical hlp ight away i you hav any vy sious sid cts, including: sizus. A vy sious allgic action to this dug is a. Howv, gt mdical hlp ight away i you notic any symptoms o a sious allgic action, including: ash, itching/swlling (spcially o th ac/tongu/thoat), sv dizzinss, toubl bathing. This is not a complt list o possibl sid cts. I you notic oth cts not listd abov, contact you docto o phamacist. Uss Medrol deutsch Mthylpdnisolon is usd to tat conditions such as athitis, blood disods, sv allgic actions, ctain cancs, y conditions, skin/kidny/intstinal/lung disass, and immun systm disods. It dcass you immun systm's spons to vaious disass to duc symptoms such as swlling, pain, and allgic-typ actions. This mdication is a coticostoid homon. Mthylpdnisolon may also b usd with oth mdications in homon disods. How to us Medrol Tak this mdication by mouth as dictd by you docto, usually with ood o milk. ollow you dosing instuctions caully. Th dosag and lngth o tatmnt a basd on you mdical condition and spons to tatmnt. Dint dosing schduls xist o this mdication. I you a not taking th sam dos ach day o...Sid cts Nausa, vomiting, hatbun, hadach, dizzinss, toubl slping, apptit changs, incasd swating, o acn may occu. I any o ths cts psist o wosn, tll you docto o phamacist pomptly. mmb that you docto has pscibd this mdication bcaus h o sh has judgd that th bnit to you is gat than th isk o sid cts. Many popl using this mdication do not hav sious sid cts. This mdication may mak you blood suga lvl is, which can caus o wosn diabts. Tll you docto immdiatly i you dvlop symptoms o high blood suga, such as incasd thist and uination. I you alady hav diabts, b su to chck you blood sugas gulaly. You docto may nd to adjust you diabts mdication, xcis pogam, o dit...o Halthca Possionals Applis to mthylpdnisolon: compounding powd, injctabl powd o injction, injctabl suspnsion, oal tablt Medrol Advs cts hav occud lss quntly whn minimum dosags hav bn administd. Advs cts o coticostoid thapy may b subdividd into thos associatd with shot-tm thapy (to th wks) and thos o long-tm thapy (> th wks). Shot-tm cts hav includd sodium tntion-latd wight gain and luid accumulation, hypglycmia and glucos intolanc, hypokalmia, gastointstinal upst and ulcation, vsibl dpssion o th hypothalamic-pituitay-adnal (HPA) axis, and mood changs anging om mild uphoia and insomnia to nvousnss, stlssnss, mania, catatonia, dpssion, dlusions, hallucinations, and violnt bhavio. Long-tm cts hav includd HPA suppssion, Cushingoid appaanc, hisutism o viilism, impotnc, and mnstual igulaitis, pptic ulc disas, cataacts and incasd intaocula pssu/glaucoma, myopathy, ostopoosis, and vtbal compssion actus. Cadiovascula Cadiovascula sid cts hav includd hyptnsion and congstiv hat ailu du to long-tm luid tntion as wll as dict vascula cts. Badycadia, cadiac ast, cadiac ahythmias, cadiac nlagmnt, ciculatoy collaps, at mbolism, myocadial uptu ollowing cnt myocadial inaction, syncop, tachycadia, thombombolism, thombophlbitis, and vasculitis hav also bn potd. Hyptnsion has bn associatd with long-tm thapy with coticostoids and is thought to b du to luid tntion. ndocin Coticostoid thapy may induc glucos intolanc by ducing th utilization o glucos in tissus and incasing hpatic glucos output. Patints on altnat day thapy may xhibit signiicantly high sum glucos on th day mthylpdnisolon (th activ ingdint containd in Mdol) is takn. Diabts mllitus quiing dit modiications and hypoglycmic agnts has dvlopd in som patints. Adnal suppssion can psist o up to twlv months at long-tm coticostoid thapy. Adnal suppssion may b ducd by giving coticostoids onc a day o onc vy oth day. At coticostoid thapy has bn tapd, supplmntal coticostoid thapy duing tims o physical stss may b quid. ndocin sid cts hav includd dcasd glucos tolanc and hypglycmia sulting in diabts-lik symptoms. Hypothalamic-pituitay-adnal activity has bn suppssd 12 months o mo ollowing long-tm coticostoid administation. Cushingoid appaanc commonly has occud with chonic thapy. Hisutism o viilism, impotnc, and mnstual igulaitis may occu. Glycosuia, hisutism, and hyptichosis hav also bn potd. Gastointstinal Medrol Gastointstinal cts most commonly occuing duing coticostoid thapy hav includd nausa, vomiting, dysppsia, and anoxia. Pptic ulc disas has bn associatd with long-tm coticostoid thapy, but is lativly uncommon. outin pophylactic thapy is not waantd in all individuals. Aluminum/magnsium containing antacids gnally hav bn usd to manag GI complaints without signiicant dug intactions. Gastointstinal sid cts hav includd gastointstinal upst, nausa, vomiting, and pptic ulc disas. Pancatitis, ulcativ sophagitis, gastointstinal poation and hmohag hav also bn potd. Additionally, abdominal distntion, bowl/bladd dysunction (at intathcal administation), incasd apptit, and poation o th small and lag intstin (paticulaly in patints with inlammatoy bowl disas) hav bn potd. Mtabolic Mtabolic sid cts hav includd hypnatmia (a), hypokalmia, luid tntion, ngativ nitogn balanc and incas in blood ua nitogn concntation. Musculoskltal Musculoskltal sid cts hav includd myopathy, ostopoosis, vtbal compssion actus, tndon uptu (paticulaly th Achills tndon), and asptic ncosis o bon hav occud duing coticostoid thapy. Asptic ncosis most otn has actd th moal had. Chacot-lik athopathy, loss o muscl mass, muscl waknss, ostopoosis, pathologic actu o long bons, and vtbal compssion actus has also bn potd. Coticostoid myopathy psnting as waknss and wasting o th poximal limb and gidl muscls has occud, but has gnally solvd ollowing cssation o thapy. Coticostoids inhibit intstinal absoption and incas uinay xction o calcium lading to bon soption and bon loss. Bon loss o 3% ov on ya has bn dmonstatd with pdnisolon 10 mg p day. Postmnopausal mals a at isk o loss o bon dnsity. Up to 16% o ldly patints tatd with coticostoids o 5 yas may xpinc vtbal compssion actus. On autho potd masuabl bon loss ov two yas in womn on concomitant thapy with pdnison 7.5 mg p day and tamoxin. Hmatologic Hmatologic sid cts hav includd thombocytopnia, lymphopnia, and platlt altations sulting in thombolic vnts. Immunologic Immunologic sid cts hav includd impaimnt in cll-mdiatd immunity and incasd suscptibility to bactial, vial, ungal and paasitic inctions. Immun spons to skin tsts may b suppssd. Medrol Hpatic sid cts hav includd vsibl incass in sum tansaminas and alkalin phosphatas concntations. Hpatomgaly has also b potd.[] Medrol Ocula sid cts hav includd incasd intaocula pssu, glaucoma, and postio subcapsula cataacts. In nal tansplant patints maintaind on pdnison 10 mg p day, 33% dvlopd postio subcapsula cataacts. Man tim to cataact dvlopmnt was 26 months. Incasd intaocula pssu has occud in 5% o patints. Psychiatic Psychiatic sid cts hav includd psychoss, psonality o bhavioal changs, dpssion, motional instability, uphoia, mood swings, and psychic disods. Dmatologic Dmatologic sid cts hav includd buising, cchymosis, ptchia stia, dlayd wound haling, and acn. Allgic dmatitis, cutanous and subcutanous atophy, dy scaly skin, ythma, hyppigmntation, hypopigmntation, incas swating, ash, stil abscss, stia, thin agil skin, and thinning scalp hai, and uticaia hav also bn potd. Oth Psudohumatism, o glucocoticoid-withdawal syndom not latd to adnal insuicincy has occud on withdawal o coticostoids. Patints xpincd anoxia, nausa, vomiting, lthagy, hadach, v, athalgias, myalgias and postual hypotnsion. Symptoms solvd whn coticostoid thapy was instatd. Oth sid cts hav includd a glucocoticoid withdawal syndom sn upon abupt discontinuation o coticostoid thapy that was not associatd with adnal suppssion. Oncologic spiatoy spiatoy sid cts hav includd pulmonay dma. |
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